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Comprar Kytril Online

  • €1.56
  • Disponibilidad: En stock
  • Ingrediente activo: Granisetron
Kytril es utilizado para prevenir las náuseas y los vómitos que pueden ser causados ​​por los medicamentos usados para el tratamiento del cáncer (quimioterapia o radioterapia).
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2 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €3.09 €92.63
60 píldoras €2.46 €185.27 €147.47
90 píldoras €2.25 €277.90 €202.31
120 píldoras €2.14 €370.53 €257.14
180 píldoras €2.04 €555.80 €366.83
1 mg
Nombre del producto Por píldora Por paquete  
30 píldoras €2.16 €64.86
60 píldoras €1.82 €129.72 €109.29
90 píldoras €1.71 €194.59 €153.72
120 píldoras €1.65 €259.45 €198.15
180 píldoras €1.59 €389.17 €287.02
270 píldoras €1.56 €583.76 €420.30

INDICATIONS

Kytril blocks the actions of chemicals in the body that can trigger nausea and vomiting.

INSTRUCTIONS

Take Kytril exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Kytril is usually started up to 1 hour before chemotherapy. Follow your doctor's instructions.

Measure the liquid form of Kytril with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

If you missed a dose - tell your doctor if you forget to take your dose within 1 hour before chemotherapy. Do not take extra medicine to make up the missed dose.

DOSAGE

Emetogenic Chemotherapy
The recommended adult dosage of oral KYTRIL (granisetron hydrochloride) is 2 mg once daily or 1 mg twice daily. In the 2 mg once-daily regimen, two 1 mg tablets or 10 mL of KYTRIL (granisetron) Oral Solution (2 teaspoonfuls, equivalent to 2 mg of granisetron) are given up to 1 hour before chemotherapy. In the 1 mg twice-daily regimen, the first 1 mg tablet or one teaspoonful (5 mL) of KYTRIL (granisetron) Oral Solution is given up to 1 hour before chemotherapy, and the second tablet or second teaspoonful (5 mL) of KYTRIL (granisetron) Oral Solution, 12 hours after the first. Either regimen is administered only on the day(s) chemotherapy is given. Continued treatment, while not on chemotherapy, has not been found to be useful.

Pediatric Use
Safety and effectiveness in pediatric patients have not been established.

Radiation (Either Total Body Irradiation or Fractionated Abdominal Radiation)
The recommended adult dosage of oral KYTRIL (granisetron) is 2 mg once daily. Two 1 mg tablets or 10 mL of KYTRIL (granisetron) Oral Solution (2 teaspoonfuls, equivalent to 2 mg of granisetron) are taken within 1 hour of radiation.

STORAGE

Store Kytril at room temperature away from moisture and heat.

SAFETY INFORMATION

You should not use Kytril if you are allergic to granisetron or to similar medicines such as dolasetron (Anzemet), ondansetron (Zofran), or palonosetron (Aloxi).

Before taking Kytril, tell your doctor if you have liver disease, a heart rhythm disorder, an electrolyte imbalance (such as low levels of potassium or magnesium in your blood), or a personal or family history of Long QT syndrome.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely take Kytril:

  • liver disease;
  • a heart rhythm disorder;
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or
  • a personal or family history of Long QT syndrome.

FDA pregnancy category B. Kytril is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether granisetron passes into breast milk or if it could harm a nursing baby. Do not use Kytril without telling your doctor if you are breast-feeding a baby.

Kytril is usually started up to 1 hour before chemotherapy. Tell your doctor if you forget to take the medication within the specified amount of time before your procedure.

There may be other drugs that can interact with Kytril. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction to Kytril: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • fast or pounding heartbeats;
  • fever, body aches, flu symptoms; or
  • easy bruising or bleeding; unusual weakness.

Less serious Kytril side effects may include:

  • headache;
  • stomach pain or upset, loss of appetite;
  • diarrhea or constipation;
  • dizziness; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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Para no tener de pasar por situación adversa alguna y evitar los efectos secundarios, tendríamos de tener en cuenta las precauciones, advertencias, así como las contraindicaciones con tal de no sufrir las reacciones adversas o algunos efectos secundarios, pero algún que otro paciente hipersensible puede sufrir reacciones negativas de diferentes incidentes que luego enumeraremos. Tan pronto como observan estos efectos diríjanse o llamen al médico sin dudarlo, póngase en contacto con un doctor en línea o con su médico personal, al no ser que ocurra alguna incidencia indeseable:

Rare

  • Arm, back, or jaw pain
  • chest pain or discomfort
  • chest tightness or heaviness
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fainting
  • irregular heartbeat
  • nausea
  • shortness of breath
  • skin rash, hives, and itching
  • sweating

More Common

  • Abdominal or stomach pain
  • diarrhea
  • difficulty having a bowel movement (stool)
  • headache
  • lack or loss of strength
  • unusual tiredness or weakness
  • vomiting

Less Common

  • Blurred vision
  • fever
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • Agitation
  • dizziness
  • drowsiness
  • fear
  • heartburn
  • indigestion
  • sleepiness or unusual drowsiness
  • sour stomach
  • trouble with sleeping
  • unusual taste in the mouth
Type Small Molecule
Accession Number DB00889  (APRD01002)
Groups Approved, Investigational
Synonyms
  • granisétron
  • granisetrón
  • granisetronum
UNII WZG3J2MCOL
CAS number 109889-09-0
Weight Average: 312.417
Monoisotopic: 312.195011409
Chemical Formula C18H24N4O
InChI
InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)/t12-,13+,14-
IUPAC Name
1-methyl-N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1H-indazole-3-carboxamide
Protein binding

65%

Toxicity

LD50>2000 mg/kg (rat, oral)

Half life

4-6 hours in healthy patients, 9-12 hours in cancer patients

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